Opportunity Information: Apply for RFA HL 18 019

The funding opportunity titled "Increasing Use of Cardiac and Pulmonary Rehabilitation in Traditional and Community Settings (R61/R33)" (Funding Opportunity Number RFA HL 18 019) is a discretionary grant program from the U.S. Department of Health and Human Services through the National Institutes of Health. It is designed to support research that directly tackles a long-standing gap in care: although cardiac rehabilitation (CR) and pulmonary rehabilitation (PR) are strongly recommended for many eligible patients and are associated with better health outcomes, they are still underused in real-world settings. The program specifically calls for Phase 2 clinical trials that develop, refine, and test strategies aimed at increasing participation in CR and PR, while also documenting whether these strategies lead to meaningful improvements for patients.

The core purpose is practical and implementation-focused. Rather than simply studying CR or PR efficacy in ideal circumstances, the initiative targets approaches that can increase actual utilization among eligible patients, including those who face access barriers. A major emphasis is on reducing disparities in CR and PR use, meaning applicants are expected to think seriously about inequities tied to geography, socioeconomic status, race and ethnicity, disability, insurance coverage, or health system limitations. In addition to increasing enrollment and adherence, the initiative expects investigators to measure improvements in key clinical outcomes and patient-centered outcomes when CR and PR are delivered in both traditional settings (like hospital-based or clinic-based rehab programs) and non-traditional or community settings (which can include home-based models or other community-integrated delivery approaches).

The mechanism is an R61/R33 phased award, which typically supports a staged project structure: an initial, time-limited development or pilot phase (R61) followed by an expansion or implementation/testing phase (R33) contingent on meeting predefined milestones. In practice, this setup encourages applicants to propose innovative interventions but also requires a realistic plan for de-risking the approach early, demonstrating feasibility, and then moving into a more definitive Phase 2 trial to test the strategy more rigorously. This structure aligns with the announcement's goal of moving beyond ideas and into tested, scalable strategies that health systems and communities could realistically adopt.

The FOA encourages teams with expertise spanning cardiac rehabilitation, pulmonary rehabilitation, and implementation science, reflecting that the problem is not only clinical but also behavioral and systems-level. Applicants are encouraged to build collaborative projects that combine clinical knowledge with skills in designing and deploying real-world interventions. The announcement explicitly highlights telehealth and internet-based interventions, behavioral modification strategies, and other novel techniques for health-related interventions as promising directions. This signals strong interest in models that can extend rehab beyond traditional facilities, support patients remotely, and address practical barriers like transportation, work schedules, caregiving responsibilities, or limited local program availability.

In terms of eligibility, the program is broadly open to a wide range of applicant organizations. Eligible applicants include state, county, and city or township governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments and other tribal organizations; public housing authorities/Indian housing authorities; nonprofit organizations both with and without 501(c)(3) status (excluding institutions of higher education in those categories); for-profit organizations other than small businesses; small businesses; and other entities as described in the funding announcement's additional eligibility language. This wide eligibility footprint reinforces the program's interest in solutions that can be tested across varied settings, including academic medical centers, community-based organizations, health systems, and potentially industry partners involved in digital health or remote monitoring.

The award information provided includes an award ceiling of $500,000 and an expected number of approximately five awards. The opportunity was created on July 12, 2017, with an original closing date of October 19, 2017. The activity category is health-related research, and the CFDA numbers listed are 93.233, 93.837, 93.838, and 93.839, reflecting NIH funding streams related to heart, lung, and blood research and related public health priorities.

Overall, this FOA is aimed at generating actionable evidence about how to get more eligible patients into CR and PR, keep them engaged, and improve outcomes, particularly for populations that have historically had lower access or lower participation. The clearest fit is for projects that bring together clinical rehabilitation expertise and implementation and behavioral science to test scalable delivery strategies, including technology-enabled models and community-based approaches that can help close the gap between guideline recommendations and real-world rehabilitation use.

  • The Department of Health and Human Services, National Institutes of Health in the health sector is offering a public funding opportunity titled "Increasing Use of Cardiac and Pulmonary Rehabilitation in Traditional and Community Settings (R61/R33)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.233, 93.837, 93.838, 93.839.
  • This funding opportunity was created on Jul 12, 2017.
  • Applicants must submit their applications by Oct 19, 2017. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Each selected applicant is eligible to receive up to $500,000.00 in funding.
  • The number of recipients for this funding is limited to 5 candidate(s).
  • Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For profit organizations other than small businesses, Small businesses, Others (see text field entitled Additional Information on Eligibility for clarification).
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