Opportunity Information: Apply for CDC RFA PS22 2208
The Strengthening Syringe Services Programs opportunity (CDC RFA PS22-2208) is a discretionary cooperative agreement from the U.S. Department of Health and Human Services, Centers for Disease Control and Prevention (CDC), specifically through NCHHSTP. Its overall goal is to expand access to harm reduction services for people who currently inject drugs or have a history of injecting (often referred to as PWID) and, by doing so, lower the spread of infectious diseases and other serious health complications linked to injection drug use. The grant is structured around two distinct components that applicants can pursue separately or together, depending on their role, capacity, and reach.
Component 1 focuses on building and strengthening a national network of syringe services programs (SSPs). The intent is to improve communication and coordination among SSPs, other harm reduction providers, and trusted national organizations that already have a track record of improving health outcomes for people who use drugs (PWUD). In practical terms, this component is about creating the connective tissue: mechanisms for peer learning, shared problem-solving, referral pathways, consistent messaging, and collaboration across programs that often operate in challenging local environments. A major piece of Component 1 is also improving the quality of information available about SSPs nationwide. That includes surveying SSPs to better document what services they currently provide, what their staffing and operational capacity looks like, where they are struggling, and where major service gaps exist. The idea is that stronger, more complete data can guide smarter technical assistance, targeted investments, and quicker responses when outbreaks or emerging issues occur.
Component 2 is more operational and service-delivery oriented. It is designed to increase direct support and resources to SSPs so they can expand and strengthen core harm reduction activities. This includes distributing sterile injection supplies and ensuring safe disposal options for used supplies, which are foundational services for reducing unsafe injection practices and preventing transmission of bloodborne infections. Component 2 also emphasizes stronger testing, treatment, and prevention services for infectious diseases and injection-related complications. The NOFO explicitly points to viral hepatitis (HCV and HBV), hepatitis A (HAV), and HIV, as well as bacterial infections like endocarditis and other infectious complications that can result from injection drug use. Beyond infections, Component 2 supports broader efforts to mitigate other harms related to drug use, which commonly includes linkage to care and wraparound supports that reduce health risks and improve stability.
The expected results reflect both the systems-building focus of Component 1 and the frontline service expansion of Component 2. CDC anticipates improved collaboration and communication among SSPs nationwide, along with better data on SSP capacity, needs, and gaps. On the public health side, the program aims to increase access to harm reduction services, reduce unsafe injection practices, and decrease new infections of HCV, HBV, HAV, and HIV, while also lowering rates of endocarditis and other injection-associated infections. The NOFO also highlights reducing overdose rates and mortality and improving the ability of communities and programs to respond quickly and effectively to outbreaks tied to injection drug use. Taken together, the long-term aim is a stronger, better-connected SSP infrastructure across the United States, with more consistent service availability and greater readiness to address both everyday needs and public health emergencies.
Eligibility is broad and includes state, county, city, and township governments; special districts; public and state-controlled higher education institutions; private higher education institutions; federally recognized tribal governments and other tribal organizations; public housing authorities; nonprofits with or without 501(c)(3) status; for-profit organizations (other than small businesses) and small businesses; and other entities as allowed by the notice’s additional eligibility language. The funding instrument is a cooperative agreement, which generally means recipients should expect substantial involvement from CDC beyond a typical grant, often through collaboration on planning, performance monitoring, and implementation support. The opportunity was created on March 1, 2022, with an original application deadline of May 2, 2022 (11:59 pm ET). The listing indicates an expected two awards, and the award ceiling is shown as 0 in the source data, which typically signals that the ceiling was not specified in that particular summary field rather than implying no funding.Apply for CDC RFA PS22 2208
- The Department of Health and Human Services, Centers for Disease Control - NCHHSTP in the health sector is offering a public funding opportunity titled "Strengthening Syringe Services Programs" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.488.
- This funding opportunity was created on Mar 01, 2022.
- Applicants must submit their applications by May 02, 2022 Electronically submitted applications must be submitted no later than 1159 pm ET on the listed application due date.. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The number of recipients for this funding is limited to 2 candidate(s).
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For profit organizations other than small businesses, Small businesses, Others (see text field entitled Additional Information on Eligibility for clarification), Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled Additional Information on Eligibility.
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