Opportunity Information: Apply for W81XWH 22 MSRP EIRA
The Department of Defense (DoD), through the Department of the Army and the U.S. Army Medical Research Acquisition Activity (USAMRAA), offered the Multiple Sclerosis Research Program (MSRP) Early Investigator Research Award (EIRA) under Funding Opportunity Number W81XWH 22 MSRP EIRA. This opportunity is designed specifically to build and strengthen the next generation of multiple sclerosis (MS) researchers by supporting MS-focused projects led by investigators who are still in the early stages of their careers. The core idea is career development through doing real MS research: the award is meant to help an early investigator shape and carry out an independent research project, explore a focused scientific question or problem relevant to MS, and grow intellectually and professionally into a future leader in the field.
A defining feature of this award is the structured mentorship requirement. Applicants are expected to conduct the proposed research under the guidance of one or more designated mentors, which signals that the program values both scientific progress and deliberate training. Even with mentor involvement, the funding notice emphasizes that the Principal Investigator (PI) should be the primary author of all application components. In other words, the early-career applicant is expected to drive the proposal, articulate the research plan, and demonstrate ownership of the project, while mentors provide direction and support rather than writing the application on the PI's behalf.
From an administrative standpoint, the opportunity is classified as a discretionary federal assistance program in the science and technology/research and development area (CFDA number 12.420). The funding instrument types listed include both grants and cooperative agreements, indicating that awards could be structured either as more traditional grant funding or as cooperative agreements where the government may have a more active role in oversight or collaboration, depending on the specific terms of the award. The listing notes an expected total of six awards. The posted award ceiling is shown as 0, which typically indicates that the maximum award amount was not specified in the summary fields provided here (often the detailed funding announcement or program announcement contains budget limits, caps, or guidance that is not captured in the abbreviated metadata).
Eligibility is described as "unrestricted," meaning it is broadly open to applicants across entity types, subject to any clarifications that might appear in the full text under "Additional Information on Eligibility." In practice, language like this generally suggests that a wide range of organizations may apply (for example, universities, research institutes, hospitals, companies, or nonprofits), so long as they meet the program's stated requirements and any standard federal assistance eligibility rules. The opportunity was created on April 29, 2022, and the original application deadline was October 3, 2022, placing it within the FY22 cycle of the DoD MSRP.
Overall, the DoD MSRP Early Investigator Research Award is best understood as a mentored, early-career development mechanism tied to a concrete MS research project. It is aimed at helping new investigators establish themselves by proposing and executing MS-relevant research while receiving structured guidance, with the expectation that the PI takes clear intellectual ownership of the application and the work.Apply for W81XWH 22 MSRP EIRA
- The Department of Defense, Dept. of the Army -- USAMRAA in the science and technology and other research and development sector is offering a public funding opportunity titled "DoD Multiple Sclerosis, Early Investigator Research Award" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 12.420.
- This funding opportunity was created on Apr 29, 2022.
- Applicants must submit their applications by Oct 03, 2022. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The number of recipients for this funding is limited to 6 candidate(s).
- Eligible applicants include: Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled Additional Information on Eligibility.
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Multiple Sclerosis Research Program (MSRP) Early Investigator Research Award (EIRA) FAQs
What is this grant opportunity?
This opportunity is the Department of Defense (DoD) Multiple Sclerosis Research Program (MSRP) Early Investigator Research Award (EIRA), offered through the Department of the Army and the U.S. Army Medical Research Acquisition Activity (USAMRAA). It is identified under Funding Opportunity Number W81XWH 22 MSRP EIRA.
What is the main purpose of the EIRA?
The EIRA is designed to build and strengthen the next generation of multiple sclerosis (MS) researchers. It supports MS-focused projects led by investigators who are still early in their careers, with a strong emphasis on career development through conducting meaningful MS research.
Who is this award intended to support?
This award is intended for early-career investigators who are developing as independent researchers and who want to lead an MS-relevant research project while receiving structured mentorship.
What kinds of projects does the EIRA support?
The award supports MS-focused research projects where the early investigator proposes and conducts an independent research effort, explores a focused scientific question or problem relevant to MS, and develops professionally toward becoming a future leader in the field.
Is mentorship required?
Yes. A defining feature of the EIRA is the structured mentorship requirement. Applicants are expected to conduct the proposed research under the guidance of one or more designated mentors.
How many mentors can be involved?
The notice indicates that the research should be conducted under the guidance of one or more mentors, meaning applicants may propose more than one designated mentor if appropriate.
What is the expected role of the Principal Investigator (PI) versus the mentor(s)?
Even with mentor involvement, the funding notice emphasizes that the PI should be the primary author of all application components. The PI is expected to drive the proposal, clearly articulate the research plan, and demonstrate intellectual ownership of the project, while mentors provide guidance and support rather than writing the application for the PI.
What does it mean that the PI should be the primary author of the application?
It means the early-career applicant is expected to write and own the content of the application materials, including the research plan and other required components, showing that they are leading the project conceptually and practically (with mentors advising rather than taking over authorship).
Which agencies are involved in administering or offering this opportunity?
The opportunity is offered by the DoD through the Department of the Army and is associated with USAMRAA (U.S. Army Medical Research Acquisition Activity).
What is the CFDA number and program category?
The opportunity is listed as a discretionary federal assistance program in the science and technology/research and development category, with CFDA number 12.420.
What type of funding instrument is used (grant vs. cooperative agreement)?
The listing includes both grants and cooperative agreements. This means awards may be structured as traditional grant funding or as cooperative agreements where the government may have a more active role in oversight or collaboration, depending on the specific award terms.
How many awards were expected?
The listing notes an expected total of six awards.
What is the maximum award amount (award ceiling)?
The posted award ceiling is shown as 0 in the summary fields, which typically indicates the maximum award amount was not specified in the abbreviated metadata provided. Budget limits or caps, if any, may have been included in the full funding announcement rather than the summary.
Who is eligible to apply?
Eligibility is described as "unrestricted," meaning it is broadly open to applicants across entity types, subject to any clarifications that may appear in the full text under "Additional Information on Eligibility."
What does "unrestricted eligibility" mean in practice?
Based on the description provided, "unrestricted" generally suggests a wide range of organizations may be able to apply (for example, universities, research institutes, hospitals, companies, or nonprofits), as long as they meet the program requirements and standard federal assistance eligibility rules referenced by the opportunity.
When was this funding opportunity created?
The opportunity was created on April 29, 2022.
What was the application deadline?
The original application deadline was October 3, 2022.
What fiscal year cycle does this opportunity relate to?
It is described as being within the FY22 cycle of the DoD MSRP.
How should this award be understood overall?
Overall, the EIRA is a mentored early-career development mechanism tied to a concrete MS research project. It is intended to help early investigators establish themselves by proposing and executing MS-relevant research, receiving structured guidance, and clearly demonstrating leadership and ownership of the application and the work.
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| Funding Opportunity |
|---|
| DoD Multiple Sclerosis, Investigator-Initiated Research Award Apply for W81XWH 22 MSRP IIRA Funding Number: W81XWH 22 MSRP IIRA Agency: Department of Defense, Dept. of the Army -- USAMRAA Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
| DoD Multiple Sclerosis, Exploration-Hypothesis Development Award Apply for W81XWH 22 MSRP EHDA Funding Number: W81XWH 22 MSRP EHDA Agency: Department of Defense, Dept. of the Army -- USAMRAA Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
| CWMD: Academic Research Initiative (ARI) Apply for WD ARI 22 001 Funding Number: WD ARI 22 001 Agency: Department of Homeland Security, Office of Procurement Operations - Grants Division Category: Science and Technology and other Research and Development Funding Amount: $300,000 |
| CWMD: Academic Research Initiative (ARI) Apply for DHS 22 CWMD 077 001 Funding Number: DHS 22 CWMD 077 001 Agency: Department of Homeland Security, Office of Procurement Operations - Grants Division Category: Science and Technology and other Research and Development Funding Amount: $300,000 |
| Natural Resources & Threatened Endangered Species Mgmt US Army Garrison Hawaii Oahu Apply for W9126G22 2 SOI 3024 Funding Number: W9126G22 2 SOI 3024 Agency: Department of Defense, Fort Worth District Category: Science and Technology and other Research and Development Funding Amount: $30,000,000 |
| Disaster Resilience Research Grants Apply for 22 593 Funding Number: 22 593 Agency: National Science Foundation Category: Science and Technology and other Research and Development Funding Amount: $400,000 |
| Leading Engineering for America's Prosperity, Health, and Infrastructure Apply for 22 594 Funding Number: 22 594 Agency: National Science Foundation Category: Science and Technology and other Research and Development Funding Amount: $2,000,000 |
| FY22 DEFENSE ESTABLISHED PROGRAM TO STIMULATE COMPETITIVE RESEARCH (DEPSCoR) – RESEARCH COLLABORATION (RC) Apply for FOA AFRL AFOSR 2022 0006 Funding Number: FOA AFRL AFOSR 2022 0006 Agency: Department of Defense, Air Force Office of Scientific Research Category: Science and Technology and other Research and Development Funding Amount: $600,000 |
| DOD Bone Marrow Failure Investigator-Initiated Research Award Apply for W81XWH 22 BMFRP IIRA Funding Number: W81XWH 22 BMFRP IIRA Agency: Department of Defense, Dept. of the Army -- USAMRAA Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
| DOD Bone Marrow Failure Idea Development Award Apply for W81XWH 22 BMFRP IDA Funding Number: W81XWH 22 BMFRP IDA Agency: Department of Defense, Dept. of the Army -- USAMRAA Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
| FY22 DEFENSE ESTABLISHED PROGRAM TO STIMULATE COMPETITIVE RESEARCH (DEPSCoR) – CAPACITY BUILDING (CB) Apply for FOA AFRL AFOSR 2022 0007 Funding Number: FOA AFRL AFOSR 2022 0007 Agency: Department of Defense, Air Force Office of Scientific Research Category: Science and Technology and other Research and Development Funding Amount: $1,000,000 |
| DoD Combat Readiness Medical, Rapid Development and Translational Research Award Apply for W81XWH 22 S CRRP Funding Number: W81XWH 22 S CRRP Agency: Department of Defense, Dept. of the Army -- USAMRAA Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
| BJA FY 22 Justice Information Sharing Training and Technical Assistance (JIS TTA) Program Apply for O BJA 2022 171332 Funding Number: O BJA 2022 171332 Agency: Department of Justice, Bureau of Justice Assistance Category: Science and Technology and other Research and Development Funding Amount: $400,000 |
| DoD Vision, Translational Research Award Apply for W81XWH 22 VRP TRA Funding Number: W81XWH 22 VRP TRA Agency: Department of Defense, Dept. of the Army -- USAMRAA Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
| DoD Vision, Clinical Trial Award Apply for W81XWH 22 VRP CTA Funding Number: W81XWH 22 VRP CTA Agency: Department of Defense, Dept. of the Army -- USAMRAA Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
| DoD Vision, Focused Translational Team Science Award Apply for W81XWH 22 VRP FTTSA Funding Number: W81XWH 22 VRP FTTSA Agency: Department of Defense, Dept. of the Army -- USAMRAA Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
| DoD Vision, Investigator- Initiated Research Award Apply for W81XWH 22 VRP IIRA Funding Number: W81XWH 22 VRP IIRA Agency: Department of Defense, Dept. of the Army -- USAMRAA Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
| Seasonal Natural and Cultural Resources Management Program Suppport on Air Force Installations Apply for W9126G 22 2 SOI 2923 Funding Number: W9126G 22 2 SOI 2923 Agency: Department of Defense, Fort Worth District Category: Science and Technology and other Research and Development Funding Amount: $1,309,000 |
| FY 22 DNA Capacity Enhancement for Backlog Reduction (CEBR) Program (Formula) Apply for O BJA 2022 171344 Funding Number: O BJA 2022 171344 Agency: Department of Justice, Bureau of Justice Assistance Category: Science and Technology and other Research and Development Funding Amount: $3,000,000 |
| Sedimentary Geology and Paleobiology Apply for 22 597 Funding Number: 22 597 Agency: National Science Foundation Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
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